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Heart Failure Clinical Trials

Multicenter

  • Reno-Defend 1: Study to determine the best dosage, efficacy and safety of SLV320, a Selective A1 Adenosine Receptor Antagonist in patients hospitalized with acutely decompensated heart failure and kidney dysfunction. Principal Investigator: Hal Andrew Skopicki, MD
  • TRIDENT: Study of intravenous BG9928, a selective A1 Adenosine Receptor Antagonist, on fluid loss in patients admitted to the hospital with heart failure and kidney dysfunction. Principal Investigator: Hal Andrew Skopicki, MD
  • BREAK-DHF-I: Evaluation of Alagebrium for outpatients patients with diastolic heart failure. Principal Investigator: Hal Andrew Skopicki, MD
  • ATMOSPHERE: Study to evaluate aliskiren alone, aliskiren in with enalapril or enalapril alone for improving symptoms and survival in out-patients with chronic heart failure. Principal Investigator: Hal Andrew Skopicki, MD
  • ASCEND-HF: Study to evaluate Nesiritide in addition to best medical care in patients admitted to the hospital with acutely decompensated heart failure. Principal Investigator: Hal Andrew Skopicki, MD
  • BALANCE Study: Study to evaluate the use of Lixivaptan in patients admitted with heart failure and low blood levels of sodium. Principal Investigator: Hal Andrew Skopicki, MD
  • CORAL: Randomized study of renal artery stenting vs. medical management for renal artery stenosis. Principal Investigator: Allen Jeremias, MD
  • CREATE (PAS): Study of carotid artery stenting with the EV3 stent and filter in patients with symptomatic and asymptomatic carotid artery disease. Principal Investigator: Allen Jeremias, MD

Site Initiated

  • ABC-HF study: Study to determine the best dose of a beta blocker in stable outpatients with chronic heart failure. Principal Investigator: Hal Andrew Skopicki, MD
  • BodyH20: Use of a simple technique to rapidly determine the amount of fluid present on a patients body with stable heart failure. Principal Investigator: Hal Andrew Skopicki, MD
  • REACH: To determine the role of genetic analyses combined with non-invasive and portable imaging to detect the proper fluid balance in patients hospitalized with acutely decompensated heart failure. Principal Investigator: Hal Andrew Skopicki, MD
  • SEARCH-HFI: To determine the effect of direct instruction on the ability of floor nurses to manage heart failure patients hospitalized with acutely decompensated heart failure. Principal Investigator: Hal Andrew Skopicki, MD
  • SEARCH-HFII: To determine the effect of advance nursing care in the ability to manage heart failure patients hospitalized with acutely decompensated heart failure. Principal Investigator: Hal Andrew Skopicki, MD
  • EMU study: To understand to the body's response to use of a form of dialysis, ultrafiltration, for removal of fluid from a hospitalized patient with heart failure. Principal Investigator: Hal Andrew Skopicki, MD
  • BNPx3: To determine the clinical role of in-patient assessment of BNP on outcomes in heart failure patients. Principal Investigator: Hal Andrew Skopicki, MD
  • Fatigue HF: To quantify and determine the cause of fatigue in outpatients with heart failure. Principal Investigator: Hal Andrew Skopicki, MD
  • CLOUT-HFC: To determine the value of Heart Failure Center Consultation in patients with heart failure. Principal Investigator: Hal Andrew Skopicki, MD
  • SIMPLE-CHF: To establish the necessity of personalized clinical information to optimize the care of heart failure patients admitted into the hospital with acutely decompensated heart failure. Principal Investigator: Hal Andrew Skopicki, MD
  • DICE-HF: To test the ability of non-invasive impedance cardiography to predict long-term patient outcomes in patients with stable heart failure. Principal Investigator: Hal Andrew Skopicki, MD
  • OPTIMAL-HF: To test the concept that a report issued to the physician responsible for a patient's heart failure care can add calculated longevity to patients with chronic heart failure. Principal Investigator: Hal Andrew Skopicki, MD
  • PROBE: To determine predictors of lack of effect of biventricular pacing. Principal Investigators: Smadar Kort, MD and Hal Andrew Skopicki, MD